I think it's a benefit tradeoff you have to consider simply because the car you will be driving will not have a spare tire. So you either have to use runflat tires, or carry a compressor with tire sealant and hope that will work if you get a flat tire. If the hole in the tire is too big for sealant, well, you are just SOL, I suppose.
Both the '07 C6 and the '09 C6Z we have have runflat tires on them, and I have to admit they are comparatively noisy. I've had Michelin PS2s on the C5Z which are NOT run flats, and although they are quieter, I'm not sure the pain in the ass of dealing with a flat tire makes the grade for a tradeoff. Honestly, I'm seriously considering getting runflats for the C5Z next time I need tires and have pressure sensors installed. Not like I'm going to hear the tires anyway with as loud as that car is. :hehehe:
Heck, tires don't seem to last all that long on Corvettes anyway if you really drive them regularly, so I don't think it's any big deal to have runflats. They don't have enough depth of tread on them to really ever be 80K mile tires. More like 20K to 30K, it seems. So you just have to figure out what is most important to you and let that be your guide.
IMHO, of course...